{"id":352,"date":"2019-08-28T08:56:25","date_gmt":"2019-08-28T06:56:25","guid":{"rendered":"http:\/\/www.microgels.rwth-aachen.de\/wp\/?page_id=352"},"modified":"2020-07-08T10:10:50","modified_gmt":"2020-07-08T08:10:50","slug":"b5","status":"publish","type":"page","link":"https:\/\/www.microgels.rwth-aachen.de\/?page_id=352","title":{"rendered":"B5"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Anisometric microgels to construct 3D responsive macroporous matrices to direct and mechanically trigger cells <\/h2>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright size-large is-resized\"><a href=\"http:\/\/www.microgels.rwth-aachen.de\/wp-content\/uploads\/2020\/07\/B5_Logo_Neu.png\"><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/www.microgels.rwth-aachen.de\/wp-content\/uploads\/2020\/07\/B5_Logo_Neu.png\" alt=\"\" class=\"wp-image-1447\" width=\"211\" height=\"211\" srcset=\"https:\/\/www.microgels.rwth-aachen.de\/wp-content\/uploads\/2020\/07\/B5_Logo_Neu.png 382w, https:\/\/www.microgels.rwth-aachen.de\/wp-content\/uploads\/2020\/07\/B5_Logo_Neu-300x300.png 300w, https:\/\/www.microgels.rwth-aachen.de\/wp-content\/uploads\/2020\/07\/B5_Logo_Neu-150x150.png 150w\" sizes=\"auto, (max-width: 211px) 100vw, 211px\" \/><\/a><\/figure><\/div>\n\n\n\n<p>3D macroporous, responsive constructs are created via anisometric microgel assembly to actuate cells. The internal structure (nanoporosity), mechanical properties, and photo-thermal or magnetic responsiveness of the microgel building blocks will be characterized and designed for 3D cell culture. The assembled rod- and complex-shaped microgel structures will support and guide cell growth by providing native-like environments. Depending on the network\u2019s properties, microgels\u2019 chemical composition, loaded nanoparticles, and swelling properties, cells will be actuated dynamically with spatial and temporal control by the network in response to external triggers, such as light and magnetic fields. The cellular response to these forces will be analyzed to unravel mechanobiology-related questions.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Principle Investigators<\/h3>\n\n\n\n<p><strong>Wessling, Matthias, Prof. Dr.-Ing.<\/strong><br>Chair of Chemical Process Engineering (AVT\/CVT)<br>RWTH Aachen University<br>+49 241 80 95488 <br><a href=\"mailto:Matthias.Wessling@avt.rwth-aachen.de\">Matthias.Wessling@avt.rwth-aachen.de<\/a> <\/p>\n\n\n\n<p><strong>De Laporte, Laura, Prof. Dr.-Ing.<\/strong><br>Lehr- und Forschungsgebiet Polymere Biomaterialien <br>Institute of Technical and Macromolecular Chemistry <br>+49 241 80 23309<br><a href=\"mailto:delaporte@dwi.rwth-aachen.de\">delaporte@dwi.rwth-aachen.de<\/a> <\/p>\n\n\n\n<p><strong>Crassous, J\u00e9r\u00f4me, Prof. Dr.<\/strong><br>Institute of Physical Chemistry<br>RWTH Aachen University <br>+49 241 80 94741 <br><a href=\"mailto:crassous@pc.rwth-aachen.de\">crassous@pc.rwth-aachen.de<\/a>  <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Anisometric microgels to construct 3D responsive macroporous matrices to direct and mechanically trigger cells 3D macroporous, responsive constructs are created<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":334,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":""},"class_list":["post-352","page","type-page","status-publish","hentry"],"coauthors":[],"author_meta":{"author_link":"https:\/\/www.microgels.rwth-aachen.de\/?author=1","display_name":"sfb985_admin"},"relative_dates":{"created":"Posted 7 years ago","modified":"Updated 6 years ago"},"absolute_dates":{"created":"Posted on August 28, 2019","modified":"Updated on July 8, 2020"},"absolute_dates_time":{"created":"Posted on August 28, 2019 08:56","modified":"Updated on July 8, 2020 10:10"},"featured_img_caption":"","featured_img":false,"series_order":"","_links":{"self":[{"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages\/352","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=352"}],"version-history":[{"count":11,"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages\/352\/revisions"}],"predecessor-version":[{"id":1531,"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages\/352\/revisions\/1531"}],"up":[{"embeddable":true,"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages\/334"}],"wp:attachment":[{"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=352"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}