{"id":358,"date":"2019-08-28T08:57:32","date_gmt":"2019-08-28T06:57:32","guid":{"rendered":"http:\/\/www.microgels.rwth-aachen.de\/wp\/?page_id=358"},"modified":"2020-07-06T14:52:04","modified_gmt":"2020-07-06T12:52:04","slug":"c3","status":"publish","type":"page","link":"https:\/\/www.microgels.rwth-aachen.de\/?page_id=358","title":{"rendered":"C3"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Multi-functional microgels targeted towards inflammatory bowel disease (IBD) <\/h2>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright size-large is-resized\"><a href=\"http:\/\/www.microgels.rwth-aachen.de\/wp-content\/uploads\/2020\/07\/C3_Logo_Neu.png\"><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/www.microgels.rwth-aachen.de\/wp-content\/uploads\/2020\/07\/C3_Logo_Neu.png\" alt=\"\" class=\"wp-image-1450\" width=\"204\" height=\"208\" srcset=\"https:\/\/www.microgels.rwth-aachen.de\/wp-content\/uploads\/2020\/07\/C3_Logo_Neu.png 382w, https:\/\/www.microgels.rwth-aachen.de\/wp-content\/uploads\/2020\/07\/C3_Logo_Neu-295x300.png 295w\" sizes=\"auto, (max-width: 204px) 100vw, 204px\" \/><\/a><\/figure><\/div>\n\n\n\n<p>In this project, we will develop multifunctional microgels capable of scavenging inflammatory mediators as well as targeting, imaging, and protecting inflamed intestinal tissue. Functionalization of microgel with galectins and adhesion peptides will target the inflamed tissue thereby building a protective microgel layer to prevent secondary bacterial infection. Microgels with scavenging and imaging units will capture the inflammation ligand TNF\u03b1 and localize at the sites of inflammation. The ultimate goal is to generate therapeutic, diagnostic, and theranostic microgels.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Principle Investigators<\/h3>\n\n\n\n<p><strong>K\u00fchne, Alexander, Prof. Dr.<\/strong><br>Associated Scientist, Ulm University<br>DWI \u2013 Leibniz Institute for Interactive Materials<br>RWTH Aachen University<br>+49 731 50 22870 <br> <a href=\"mailto:alexander.kuehne@uni-ulm.de\">alexander.kuehne@uni-ulm.de<\/a> <\/p>\n\n\n\n<p><strong>Elling, Lothar, Prof. Dr.<\/strong><br>Helmholtz Institute for Biomedical Engineering<br>RWTH Aachen University<br> +49 241 80 28350 <br> <a href=\"mailto:l.elling@biotec.rwth-aachen.de\">l.elling@biotec.rwth-aachen.de<\/a> <\/p>\n\n\n\n<p><strong>Trautwein, Christian, Prof. Dr. med.<\/strong><br>Lehrstuhl f\u00fcr Innere Medizin<br>Uniklinik RWTH Aachen<br>+49 241 80 80866<br><a href=\"mailto:ctrautwein@ukaachen.de\">ctrautwein@ukaachen.de<\/a><\/p>\n\n\n\n<p><strong>Strnad, Pavel, Priv.-Doz. Dr. med.<\/strong><br>Lehrstuhl f\u00fcr Innere Medizin<br>Uniklinik RWTH Aachen<br>+49 241 80 35324<br><a href=\"mailto:pstrnad@ukaachen.de\">pstrnad@ukaachen.de<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Multi-functional microgels targeted towards inflammatory bowel disease (IBD) In this project, we will develop multifunctional microgels capable of scavenging inflammatory<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":336,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":""},"class_list":["post-358","page","type-page","status-publish","hentry"],"coauthors":[],"author_meta":{"author_link":"https:\/\/www.microgels.rwth-aachen.de\/?author=1","display_name":"sfb985_admin"},"relative_dates":{"created":"Posted 7 years ago","modified":"Updated 6 years ago"},"absolute_dates":{"created":"Posted on August 28, 2019","modified":"Updated on July 6, 2020"},"absolute_dates_time":{"created":"Posted on August 28, 2019 08:57","modified":"Updated on July 6, 2020 14:52"},"featured_img_caption":"","featured_img":false,"series_order":"","_links":{"self":[{"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages\/358","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=358"}],"version-history":[{"count":7,"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages\/358\/revisions"}],"predecessor-version":[{"id":1474,"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages\/358\/revisions\/1474"}],"up":[{"embeddable":true,"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages\/336"}],"wp:attachment":[{"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=358"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}