{"id":362,"date":"2019-08-28T08:58:14","date_gmt":"2019-08-28T06:58:14","guid":{"rendered":"http:\/\/www.microgels.rwth-aachen.de\/wp\/?page_id=362"},"modified":"2020-07-07T15:56:35","modified_gmt":"2020-07-07T13:56:35","slug":"c5","status":"publish","type":"page","link":"https:\/\/www.microgels.rwth-aachen.de\/?page_id=362","title":{"rendered":"C5"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Microgels for a combined enzymatic reaction and <em>in situ<\/em> extraction in liquid-liquid systems <\/h2>\n\n\n\n<p>Enzymatic\ncatalyzed reactions enable promising process routes for enantiopure components.\nShorter processing times, a reduced number of reaction steps, and a minimum\namount of waste, due to the high selectivity of the enzymes towards the target\nmolecule, are possible advantages. However, such reactions often suffer from\nequilibrium limitations and product inhibition.<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright size-large is-resized\"><a href=\"http:\/\/www.microgels.rwth-aachen.de\/wp-content\/uploads\/2020\/07\/C5_Logo_Neu.png\"><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/www.microgels.rwth-aachen.de\/wp-content\/uploads\/2020\/07\/C5_Logo_Neu.png\" alt=\"\" class=\"wp-image-1451\" width=\"198\" height=\"202\"\/><\/a><\/figure><\/div>\n\n\n\n<p>In C5 we will tackle these limitations by coupling the reaction with a microgel intensified liquid-liquid extraction (investigated in the 2<sup>nd<\/sup> funding period). By immobilizing the catalyst inside the microgel the enzymatic catalyzed reaction is located at the liquid-liquid interface. This combination of microgels and enzymes offers the possibility to intensify the reaction due to direct supply of hardly water-soluble reactants to the catalytic active center, the <em>in situ<\/em> extraction, and the catalyst recycling.<\/p>\n\n\n\n<p>To understand the different occurring effects and their interactions in the reaction-extraction system, we will investigate the fundamental phenomena across different scales. The distribution of enzymes embedded in the microgel and their activity as well as diffusional pathways of reactants inside the microgels will be investigated microscopically using superresolution fluorescence imaging techniques. Based on these results and in combination with reaction-kinetic and mass-transport measurements via single drop experiments, we finally aim at a continuous <em>in situ<\/em> extraction process.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Principle Investigators<\/h3>\n\n\n\n<p><strong>Jupke, Andreas, Prof. Dr.-Ing. <\/strong><br>AVT \u2013 Fluid Process Engineering<br>RWTH Aachen University <br>+49 241 80 95490 <br><a href=\"mailto:andreas.jupke@avt.rwth-aachen.de\">andreas.jupke@avt.rwth-aachen.de<\/a> <\/p>\n\n\n\n<p><strong>W\u00f6ll, Dominik, Prof. Dr.<\/strong> <br>Institute of Physical Chemistry<br>RWTH Aachen University<br>+49 241 80 98624<br><a href=\"mailto:woell@pc.rwth-aachen.de\">woell@pc.rwth-aachen.de<\/a>  <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Microgels for a combined enzymatic reaction and in situ extraction in liquid-liquid systems Enzymatic catalyzed reactions enable promising process routes<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":336,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":""},"class_list":["post-362","page","type-page","status-publish","hentry"],"coauthors":[],"author_meta":{"author_link":"https:\/\/www.microgels.rwth-aachen.de\/?author=1","display_name":"sfb985_admin"},"relative_dates":{"created":"Posted 7 years ago","modified":"Updated 6 years ago"},"absolute_dates":{"created":"Posted on August 28, 2019","modified":"Updated on July 7, 2020"},"absolute_dates_time":{"created":"Posted on August 28, 2019 08:58","modified":"Updated on July 7, 2020 15:56"},"featured_img_caption":"","featured_img":false,"series_order":"","_links":{"self":[{"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages\/362","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=362"}],"version-history":[{"count":11,"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages\/362\/revisions"}],"predecessor-version":[{"id":1523,"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages\/362\/revisions\/1523"}],"up":[{"embeddable":true,"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages\/336"}],"wp:attachment":[{"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=362"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}