{"id":959,"date":"2020-07-07T09:30:17","date_gmt":"2020-07-07T07:30:17","guid":{"rendered":"http:\/\/www.microgels.rwth-aachen.de\/?page_id=959"},"modified":"2020-07-07T09:29:35","modified_gmt":"2020-07-07T07:29:35","slug":"c8n","status":"publish","type":"page","link":"https:\/\/www.microgels.rwth-aachen.de\/?page_id=959","title":{"rendered":"C8N"},"content":{"rendered":"\n

Microgel-cell interactions<\/h2>\n\n\n\n
\"\"<\/a><\/figure><\/div>\n\n\n\n

In this project, we will investigate the interactions of soft microgels in the size range of 40\u2013500 nm radius with cells. Through the preparation of microgels that allow the alteration of their structural features non-invasively, on-line, and during their observation, we aim to gain a conceptual understanding of how their properties affect their adsorption to cell surfaces as well as their translocation into cells and, ultimately, their fate inside the cell. We will initially use human embryonic kidney (HEK293) and immortal human cervical cancer cells (HeLa) as both are representative and well-described human cellular model systems. Depending on the progress of parallel SFB projects, we are prepared to include additional relevant cell types in our experimental portfolio. <\/p>\n\n\n\n

Principle Investigators<\/h3>\n\n\n\n

Richtering, Walter, Prof. Dr. <\/strong>
Institute of Physical Chemistry
RWTH Aachen University
+49 241 80 94760
richtering@rwth-aachen.de<\/a> <\/p>\n\n\n\n

Spehr, Marc, Prof. Dr.<\/strong>
Institute for Biology II \/ Dept. Chemosensation
RWTH Aachen University
+49 241 80 20802
m.spehr@sensorik.rwth-aachen.de<\/a><\/p>\n\n\n\n

G\u00f6stl, Robert, Dr.<\/strong>
DWI \u2013 Leibniz Institute for Interactive Materials
RWTH Aachen University
+49 241 80 23345
goestl@dwi.rwth-aachen.de<\/a> <\/p>\n","protected":false},"excerpt":{"rendered":"

Microgel-cell interactions In this project, we will investigate the interactions of soft microgels in the size range of 40\u2013500 nm<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":336,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":""},"class_list":["post-959","page","type-page","status-publish","hentry"],"coauthors":[],"author_meta":{"author_link":"https:\/\/www.microgels.rwth-aachen.de\/?author=1","display_name":"sfb985_admin"},"relative_dates":{"created":"Posted 6 years ago","modified":"Updated 6 years ago"},"absolute_dates":{"created":"Posted on July 7, 2020","modified":"Updated on July 7, 2020"},"absolute_dates_time":{"created":"Posted on July 7, 2020 09:30","modified":"Updated on July 7, 2020 09:29"},"featured_img_caption":"","featured_img":false,"series_order":"","_links":{"self":[{"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages\/959","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=959"}],"version-history":[{"count":5,"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages\/959\/revisions"}],"predecessor-version":[{"id":1487,"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages\/959\/revisions\/1487"}],"up":[{"embeddable":true,"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages\/336"}],"wp:attachment":[{"href":"https:\/\/www.microgels.rwth-aachen.de\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=959"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}