{"id":1642,"date":"2020-09-10T12:43:09","date_gmt":"2020-09-10T10:43:09","guid":{"rendered":"http:\/\/www.microgels.rwth-aachen.de\/?p=1642"},"modified":"2020-09-10T12:43:09","modified_gmt":"2020-09-10T10:43:09","slug":"nanoparticles-in-the-biological-context-surface-morphology-and-protein-corona-formation","status":"publish","type":"post","link":"https:\/\/www.microgels.rwth-aachen.de\/?p=1642","title":{"rendered":"Nanoparticles in the biological context: surface morphology and protein corona formation"},"content":{"rendered":"\n
\"\"<\/a><\/figure>\n\n\n\n

In a recent concept article published in Small<\/em>, Richtering, Alberg and Zentel have summarized existing data with the aim to explain the differences in nanoparticles and their influence on the interaction with plasma proteins from a physico-chemical perspective. The authors conclude that the difference between a strongly hydrated\/swollen polymer shell versus a sharp \u201chard\u201d surface and its accessibility are especially relevant for biomedical applications.<\/p>\n\n\n\n

Walter Richtering, Irina Alberg and Rudolf Zentel<\/em><\/p>\n\n\n\n

Small<\/em> 2020<\/strong>, 2002162, DOI: 10.1002\/smll.202002162<\/a> <\/p>\n\n\n\n

The authors’ motivation to look deeper into this topic arose from a recent finding that not all nanosized objects form a so called protein corona in the presence of plasma proteins. Read more on Advanced Science News<\/em>:<\/p>\n\n\n\n

\n
New method gives more accurate picture of nanoparticle surfaces<\/a><\/blockquote>